2,152 research outputs found
Scaling in the Lattice Gas Model
A good quality scaling of the cluster size distributions is obtained for the
Lattice Gas Model using the Fisher's ansatz for the scaling function. This
scaling identifies a pseudo-critical line in the phase diagram of the model
that spans the whole (subcritical to supercritical) density range. The
independent cluster hypothesis of the Fisher approach is shown to describe
correctly the thermodynamics of the lattice only far away from the critical
point.Comment: 4 pages, 3 figure
Fixed-point elimination in the intuitionistic propositional calculus
It is a consequence of existing literature that least and greatest
fixed-points of monotone polynomials on Heyting algebras-that is, the algebraic
models of the Intuitionistic Propositional Calculus-always exist, even when
these algebras are not complete as lattices. The reason is that these extremal
fixed-points are definable by formulas of the IPC. Consequently, the
-calculus based on intuitionistic logic is trivial, every -formula
being equivalent to a fixed-point free formula. We give in this paper an
axiomatization of least and greatest fixed-points of formulas, and an algorithm
to compute a fixed-point free formula equivalent to a given -formula. The
axiomatization of the greatest fixed-point is simple. The axiomatization of the
least fixed-point is more complex, in particular every monotone formula
converges to its least fixed-point by Kleene's iteration in a finite number of
steps, but there is no uniform upper bound on the number of iterations. We
extract, out of the algorithm, upper bounds for such n, depending on the size
of the formula. For some formulas, we show that these upper bounds are
polynomial and optimal
Comparison of Italian and Hungarian Black Spot Ranking
AbstractBlack spot ranking is an important tool for finding the sites with potential safety improvement on the road network. The EU Directive on Road Infrastructure Safety Management also demands the ranking of high accident concentration sites. This paper gives an introduction to localizing high accident concentration sites and the indicators used by Italy and Hungary. Accident and traffic volume data are gathered for motorway sections from both countries. Safety ranking is made using two conventional indicators, absolute number of accidents and accident rate. A more sophisticated ranking using the Empirical Bayes method is applied. Expected average crash frequency with Empirical Bayes adjustment is calculated. Based on the estimation of the crash frequency, the Critical Crash Rate (CCR) was added to identify and rank black spots. This additional performance measure is able to take into account traffic volume as required by the EU Directive. Results of the Empirical Bayes method are compared with the conventional procedures. It is concluded that the results are not comparable; inasmuch as there are modifications in the order of black spots. Based on the comparison of results recommendations are given to change the practice in both countries
Statistical evolution of isotope composition of nuclear fragments
Calculations within the statistical multifragmentation model show that the
neutron content of intermediate mass fragments can increase in the region of
liquid-gas phase transition in finite nuclei. The model predicts also
inhomogeneous distributions of fragments and their isospin in the freeze-out
volume caused by an angular momentum and external long-range Coulomb field.
These effects can take place in peripheral nucleus-nucleus collisions at
intermediate energies and lead to neutron-rich isotopes produced in the
midrapidity kinematic region.Comment: 14 pages with 4 figures. GSI preprint, Darmstadt, 200
Isotopic composition of fragments in multifragmentation of very large nuclear systems: effects of the chemical equilibrium
Studies on the isospin of fragments resulting from the disassembly of highly
excited large thermal-like nuclear emitting sources, formed in the ^{197}Au +
^{197}Au reaction at 35 MeV/nucleon beam energy, are presented. Two different
decay systems (the quasiprojectile formed in midperipheral reactions and the
unique source coming from the incomplete fusion of projectile and target in the
most central collisions) were considered; these emitting sources have the same
initial N/Z ratio and excitation energy (E^* ~= 5--6 MeV/nucleon), but
different size. Their charge yields and isotopic content of the fragments show
different distributions. It is observed that the neutron content of
intermediate mass fragments increases with the size of the source. These
evidences are consistent with chemical equilibrium reached in the systems. This
fact is confirmed by the analysis with the statistical multifragmentation
model.Comment: 9 pages, 4 ps figure
Simultaneous targeting of Eph receptors in glioblastoma
Eph tyrosine kinase receptors are frequently overexpressed and functional in many cancers, and they are attractive candidates for targeted therapy. Here, we analyzed the expression of Eph receptor A3, one of the most up-regulated factors in glioblastoma cells cultured under tumorsphere-forming conditions, together with EphA2 and EphB2 receptors. EphA3 was overexpressed in up to 60% of glioblastoma tumors tested, but not in normal brain. EphA3 was localized in scattered areas of the tumor, the invasive ring, and niches near tumor vessels. EphA3 co-localized with macrophage/leukocyte markers, suggesting EphA3 expression on tumor-infiltrating cells of bone marrow origin. We took advantage of the fact that ephrinA5 (eA5) is a ligand that binds EphA3, EphA2 and EphB2 receptors, and used it to construct a novel targeted anti-glioblastoma cytotoxin. The eA5-based cytotoxin potently and specifically killed glioblastoma cells with an IC(50) of at least 10(â11) M. This and similar cytotoxins will simultaneously target different compartments of glioblastoma tumors while mitigating tumor heterogeneity
Analysis of fragment yield ratios in the nuclear phase transition
The critical phenomena of the liquid-gas phase transition has been
investigated in the reactions 78,86Kr+58,64Ni at beam energy of 35 MeV/nucleon
using the Landau free energy approach with isospin asymmetry as an order
parameter. Fits to the free energy of fragments showed three minima suggesting
the system to be in the regime of a first order phase transition. The relation
m =-{\partial}F/{\partial}H, which defines the order parameter and its
conjugate field H, has been experimentally verified from the linear dependence
of the mirror nuclei yield ratio data, on the isospin asymmetry of the source.
The slope parameter, which is a measure of the distance from a critical
temperature, showed a systematic decrease with increasing excitation energy of
the source. Within the framework of the Landau free energy approach, isoscaling
provided similar results as obtained from the analysis of mirror nuclei yield
ratio data. We show that the external field is primarily related to the minimum
of the free energy, which implies a modification of the source concentration
\Delta used in isospin studies
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